I've got a lot of respect for Huskies. They run across Alaska (I'm not even sure I could do that) and they seem to be pleasant enough while also being big enough that I wouldn't one one in my apartment complex. Unfortunately, running across barren wilderness isn't an event in the Murphspot Mascot Bracket Challenge. I'm a man of science and if there's one immutable law of the universe, it's that if you put a cougar and a husky in a cage, the husky's not walking out.
Brigham Young moves on.
#5 Purdue Boilermakers vs. #13 Mississippi State Bulldogs
Purdue always wrecks this. There's not much that's going to stand up to a train, and since life isn't a heart-warming children's movie in which animals can talk and may or may not wear conductor hats, there's not a whole lot a bulldog is going to be able to do to a train. I could ease up and go with the idea that the boilermaker is the guy that makes the boiler, or that it's referring to whiskey and a beer, but a bulldog's not going to be able to do much to those things either. Purdue advances.
#11 Utah State Aggies vs. #3 Missouri Tigers
I'm sensing that we're going to come to a tiger bottleneck at some point and I'm going to have to decide between which one of the thirty tigers is going to be superior. Unfortunately, I can't deal with that here. I don't care how much agricultural science you know, a tiger isn't something you want to be in a deathmatch with. Missouri goes on.
#7 California Golden Bears vs. #2 Memphis Tigers
Didn't I just have a Bear/Tiger matchup last round? Cal's bear is a lot less tumor-y and seems to have a snarl, which to me suggests ferocity, while the Memphis tiger appears to be miming driving.
Your mascot is less likely to win a fight if its "lunging" posture is the same as its "Mario Kart" posture.
While I'm not sure bears and tigers tend to hang out a lot, and therefore have no way to confirm which would win in this matchup, I'm going to say that Cal advances.